High-resolution electron microscopy sheds light on the cellular responses to stress

An international team led by researchers from the University Medical Center Göttingen (UMG), Germany, has used advanced electron microscopy technologies to capture key cellular mechanisms of stress resistance with near-atomic precision. They were able to show that the protein mHsp60, which helps other proteins to adopt their functional form, remodels its structure under stress conditions and thereby increases its activity to ensure mitochondrial functionality.